Ni and NiO Nanoparticles Decorated Metal-Organic Framework Nanosheets: Facile Synthesis and High-Performance Nonenzymatic Glucose Detection in Human Serum

Yun Shu, Yan Yan, Jingyuan Chen,Qin Xu,Huan Pang,*Xiaoya Hu*

School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China

Abstract:Ni-MOF (metal-organic framework)/Ni/NiO/carbon frame nanocomposite was formed by combing Ni, NiO nanoparticles, C frame with Ni-MOF using an efficient one-step calcination method. The morphology and structure of Ni-MOF/Ni/NiO/C nanocomposite were characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS),X-ray diffraction (XRD) and energy disperse spectroscopy (EDS) mapping. Ni-MOF/Ni/NiO/C nanocomposites were immobilized onto glassy carbon electrodes (GCEs) with Nafion film to construct high performance nonenzymatic glucose and H₂O₂electrochemical sensors. Cyclic voltammetric (CV) study showed Ni-MOF/Ni/NiO/C nanocomposite displayed better electrocatalytic activity towards glucose oxidation compared with Ni-MOF. Amperometric study indicated the glucose sensor displayed high performance, offering a low detection limit (0.8 μM), a high sensitivity of 367.45 mA•M⁻¹•cm⁻²and a wide linear range (from 4 μM to 5664 μM). Importantly, good reproducibility, long-time stability and excellent selectivity were obtained within the as-fabricated glucose sensor. Furthermore, the constructed high performance sensor was utilized to monitor the glucose levels in human serum and satisfactory results were obtained. It demonstrated the Ni-MOF/Ni/NiO/C nanocomposite can be used as a good electrochemical sensing material in practical biological applications.

ACS Applied Materials & Interfaces,DOI:10.1021/acsami.7b07501. IF=7.504.

文章链接:http://pubs.acs.org/doi/abs/10.1021/acsami.7b07501